An accident involving a genetically altered version of the SARS-CoV-2 virus highlights the risks of coronavirus research and the need for better oversight and transparency of lab research involving dangerous pathogens. […]
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An accident involving a genetically altered version of the SARS-CoV-2 virus highlights the risks of coronavirus research and the need for better oversight and transparency of lab research involving dangerous pathogens. […] A new wave of second-generation GE strategies are being used to push risky biotechnological solutions to malaria and locust infestations in Africa, diverting attention and investment away from more effective sovereign systemic solutions to overcome ecological, economic and health crises. […] CRISPR gene editing in rice varieties caused undesirable and unintended on-target and off-target mutations, according to a recent study. […] Research has found that the standard gene-editing tool, CRISPR-Cas9, frequently produces a type of DNA mutation that ordinary genetic analysis misses, suggesting that gene-editing is more error-prone than previously thought. […] To control the risks of gene drives, ‘cut-off criteria’ need to be defined to prevent the uncontrolled spread of genetically engineered gene drive organisms. […] A report endorsed by eight European environmental agencies has been published on the implications on the environment and nature conservation of gene drive organisms. […] US FDA scientists report that the gene editing process to produce hornless cattle resulted in unintended alterations at a genome-edited target site, and say this is a reason why regulatory oversight of intentional genomic alterations in animals is needed. […] A study has found that CRISPR-Cas9 edits intended to knock out the function of a gene fail to do so. Functional proteins are still produced from the damaged genes, which can result in the production of gene-edited plants that are toxic or allergenic. […] The European Parliament has passed a resolution calling on the European Commission and Member States to call for a global moratorium on gene drive releases into nature, including field trials. […] A new complex technique called ‘prime editing’ is touted to be far more precise than the CRISPR gene-editing tool, but in all likelihood, the same undesirable off-target and on-target effects will occur. […] |
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