Prime Editing Does Not Solve the Problem of Unintended Effects

A new complex technique called ‘prime editing’ is touted to be far more precise than the CRISPR gene-editing tool, but in all likelihood, the same undesirable off-target and on-target effects will occur. […]

Serious Lack of Regulatory Oversight Over Releases of Nucleic Acids and Proteins into the Environment

New technologies allow nucleic acids and proteins to be delivered to cells, tissues and organisms in the open environment. However, the current lack of regulatory oversight could lead to either dual use appropriation or unintended harm to human health or the environment. […]

Serious Threats Posed by Gene Drives for Conservation

Gene drives proposed for conservation purposes pose serious threats because their implementation could have far-reaching unintended consequences and could trigger irremediable modification of the natural environment. […]

Legal and Regulatory Issues Relevant to Gene Drive Organisms

There is an urgent need for effective international and legally binding regulation of gene drive organisms (GDOs). […]

Transferring the Laboratory to the Wild: An Emerging Era of Environmental Genetic Engineering

New GE techniques such as genome editing and new delivery techniques have facilitated an emerging trend to genetically engineer organisms in the wild, essentially converting the environment into the laboratory. […]

Gene-Editing Can Insert Unwanted DNA

Researchers have discovered that standard methods of animal and plant gene-editing can introduce DNA from unexpected sources. […]

Genome-Edited Hornless Cattle Found to Have Unintended Antibiotic Resistance Genes

New research published by US Food and Drug Administration scientists has discovered foreign DNA inadvertently introduced into the genomes of genome-edited animals, dealing a significant blow to the biotech industry’s claims that no regulation of such organisms is necessary. […]

Claims of Safety and Sustainability of SynBio “Impossible Burger” Questioned

Products of synthetic biology, such as the “Impossible Burger”, may have health, environmental and socioeconomic impacts that need to be fully assessed for safety and sustainability. […]

Gene-editing Fails to Confer Virus Resistance but Develops Mutated Viruses in Cassava

An attempt to create virus-resistant cassava using gene editing not only failed to achieve such resistance but resulted in the propagation of mutated CRISPR-resistant viruses under controlled laboratory conditions. […]

New Book: Gene Drives – Legal and Regulatory Issues

New TWN book on the legal and regulatory aspects relating to gene drive organisms (GDOs). […]